Hemorrhagic Ovarian Cyst: Ultrasound Appearance, Endometrioma Differential, O-RADS and Follow-up
The reticular pattern and retracted clot of a hemorrhagic ovarian cyst, how to tell it from an endometrioma, the O-RADS category and follow-up by size and menopausal status.
This article is part of the guide Gynecologic ultrasound: the complete guide, from uterus to ovaries.
A typical hemorrhagic ovarian cyst appears as a unilocular cyst with no internal vascularity and a reticular fibrin pattern or retracted clot, and in premenopausal patients it is O-RADS 2 when it measures less than 10 cm. It is a common benign finding in reproductive age, but it can be mistaken for an endometrioma or a solid lesion. The report must state why the cyst is typical, because that is what avoids unnecessary workup.
Hemorrhagic ovarian cyst: the typical appearance
- Reticular pattern: fine interlacing fibrin strands with no Doppler flow.
- Retracted clot: solid-looking area with no flow and concave borders. A true mural nodule usually has a convex border.
- Unilocular with no internal vascularity: both are part of the O-RADS definition.
- Acute phase: the cyst may be filled with low-level echoes and mimic a solid lesion. Preserved through-transmission and negative Doppler help.
At least one of the two patterns (reticular or retracted clot) must be present. Without them, the cyst is not classified as a typical hemorrhagic cyst.
Differential with endometrioma
| Typical hemorrhagic cyst | Typical endometrioma | |
|---|---|---|
| Content | Reticular or retracted clot | Homogeneous low-level echoes (ground glass) |
| Locules | Unilocular | Up to 3 locules |
| Wall | Thin | Smooth; may have punctate echogenic foci |
| Internal flow | Absent | Absent |
| Course | Usually regresses within weeks | Persists |
The two can look alike, especially when a hemorrhagic cyst is filled with fine echoes. In that doubt, short-term follow-up settles it: the hemorrhagic cyst regresses or changes, and the endometrioma stays. O-RADS gives 2 to 3 months; other references cite 6 to 12 weeks.
Other differentials: dermoid (hyperechoic nodule, shadowing, echogenic lines and dots) and neoplasm (solid component with flow, vascularized septa, irregular wall, ascites).
O-RADS and follow-up
Under O-RADS US v2022, both are classic benign lesions: O-RADS 2 below 10 cm and O-RADS 3 at 10 cm or more.
| Setting | Typical hemorrhagic cyst | Typical endometrioma |
|---|---|---|
| Premenopausal | Up to 5 cm: no management. Above 5 and below 10 cm: ultrasound in 2 to 3 months | Below 10 cm: if not excised, ultrasound in 12 months |
| Early postmenopausal (under 5 years) | Below 10 cm: ultrasound in 2 to 3 months, ultrasound specialist or MRI | Below 10 cm, at initial exam: same options; then, if not excised, ultrasound in 12 months |
| Late postmenopausal (5 years or more) | Should not occur: recategorize using lexicon descriptors | As above |
In all cases, gynecology input is added as needed. O-RADS notes a higher malignancy risk in endometriomas after menopause and when present for more than 10 years.
What the report should include
- Side, measurements and internal pattern (reticular or retracted clot).
- Absence of internal vascularity on Doppler.
- O-RADS category, with the menopausal status considered.
- Follow-up according to size and menopausal status.
- Free fluid and its appearance, in a patient with pain.
Common mistakes
- Calling it a "complex cyst" without describing the pattern.
- Reporting a retracted clot as a mural nodule without using Doppler.
- Requesting follow-up for a typical hemorrhagic cyst up to 5 cm in a premenopausal patient.
- Keeping the hemorrhagic label in late postmenopause.
- Labeling a cyst with fine echoes as an endometrioma at first exam without considering follow-up.
See also our articles on O-RADS, ovarian torsion and deep endometriosis mapping.
How Laudário helps
In the female pelvis templates of Laudário, on the ovaries tab:
- Typical hemorrhagic cyst option, with reticular or retracted clot internal pattern.
- Measurements and volume in the lesion fields, with the report sentence built from them.
- O-RADS category assigned by the largest diameter: 2 below 10 cm and 3 from 10 cm.
- Typical endometrioma option alongside it, to keep the differential clear.
Try it for 15 days free, no credit card required.
References
- American College of Radiology. O-RADS US v2022 Assessment Categories.
- Strachowski LM, et al. O-RADS US v2022: An Update from the American College of Radiology's Ovarian-Adnexal Reporting and Data System US Committee. Radiology 2023;308(3):e230685.
- Radiology Assistant. Roadmap to evaluate ovarian cysts.